SCHEMBL6583597

SCHEMBL6583597

CCC(C)(C)C(C)(C)c1ccc2[nH]nnc2c1-c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.33
AKT2 P31751 1/20 0.33
TP53 P04637 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27537520 0.84 AKT2 (0.39) CHEK1AKT2L3MBTL1
SCHEMBL28484764 0.81 AKT2 (0.36) CHEK1AKT2
SCHEMBL27770481 0.73 CHEK1 (0.32) CHEK1AKT2
SCHEMBL28235005 0.72 AKT2 (0.36) CHEK1AKT2TP53L3MBTL1
SCHEMBL29421033 0.72 AKT2 (0.44) CHEK1AKT2TP53L3MBTL1
SCHEMBL29359068 0.72 CHEK1 (0.37) CHEK1AKT2
SCHEMBL1462356 0.72 AKT2 (0.44) CHEK1AKT2TP53L3MBTL1
SCHEMBL80394 0.72 CHEK1 (0.37) CHEK1AKT2
SCHEMBL6897857 0.71 CHEK1 (0.36) CHEK1AKT2
SCHEMBL8836008 0.71 CHEK1 (0.36) CHEK1AKT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2885355-A1 STABLE UV ABSORBER COMPOSITION BASF SE (DE) 2015-06-24 EP disclosed
WO-2014026925-A1 STABLE UV ABSORBER COMPOSITION BASF SE (DE) 2014-02-20 WO disclosed
EP-1414799-A2 HINDERED AMINE LIGHT STABILIZERS BASED ON MULTI-FUNCTIONAL CARBONYL COMPOUNDS AND METHODS OF MAKING SAME CYTEC TECHNOLOGY CORP. (US) 2004-05-06 EP disclosed
WO-2002057232-A2 HINDERED AMINE LIGHT STABILIZERS BASED ON MULTI-FUNCTIONAL CARBONYL COMPOUNDS AND METHODS OF MAKING SAME CYTEC TECHNOLOGY CORP. (US) 2002-07-25 WO disclosed