SCHEMBL27770481

SCHEMBL27770481

CCC(C)(C)c1cc2[nH]nnc2c(-c2ccccc2)c1C(C)(C)CC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.32
AKT2 P31751 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28971638 0.82 AKT2 (0.36) CHEK1AKT2
SCHEMBL28868747 0.75 DPP4 (0.35) CHEK1AKT2
SCHEMBL28295043 0.74 TSHR (0.31) CHEK1AKT2
SCHEMBL6583597 0.73 CHEK1 (0.33) CHEK1AKT2
SCHEMBL27537520 0.72 AKT2 (0.39) CHEK1AKT2
SCHEMBL28448937 0.70 TRPA1 (0.33)
SCHEMBL28473114 0.70 KIF11 (0.33)
SCHEMBL28401801 0.69
SCHEMBL28484764 0.69 AKT2 (0.36) CHEK1AKT2
SCHEMBL8844814 0.68 AKT2 (0.41) CHEK1AKT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101495591-B Silane functional adhesive composition and method of bonding a window to a substrate without a primer DOW GLOBAL TECHNOLOGIES INC 2011-11-16 CN disclosed
CN-101495591-A Silane functional adhesive composition and method of bonding a window to a substrate without a primer DOW GLOBAL TECHNOLOGIES INC (US) 2009-07-29 CN disclosed