SCHEMBL6583736

SCHEMBL6583736

CS(=O)(=O)c1ccc(-c2oc(OC(=O)O)cc(=O)c2Oc2ccc(F)cc2F)cc1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 20/20 0.71
PTGS1 P23219 11/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5097605 0.86 PTGS2 (0.74) PTGS2PTGS1
SCHEMBL5097621 0.84 PTGS2 (0.74) PTGS2PTGS1
SCHEMBL1376884 0.83 PTGS2 (1.00) PTGS2PTGS1
SCHEMBL6580476 0.83 PTGS2 (0.78) PTGS2PTGS1
SCHEMBL5100505 0.82 PTGS2 (0.77) PTGS2PTGS1
SCHEMBL5097510 0.81 PTGS2 (0.76) PTGS2PTGS1
SCHEMBL5107065 0.79 PTGS2 (0.73) PTGS2PTGS1
SCHEMBL6580323 0.79 PTGS2 (0.70) PTGS2PTGS1
SCHEMBL5097668 0.76 PTGS2 (0.72) PTGS2PTGS1
SCHEMBL29080599 0.75 PTGS2 (0.74) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1263751-B1 2-PHENYLPYRAN-4-ONE DERIVATIVES ALMIRALL PRODESFARMA AG (CH) 2004-06-16 EP claimed