Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1770261 | 0.84 | MEN1 (0.46) | DAOPOLBMEN1CYP1A2KMT2A | |
| SCHEMBL4704534 | 0.84 | GRIA2 (0.50) | DAOPOLBMEN1CYP1A2KMT2A | |
| SCHEMBL11407185 | 0.81 | L3MBTL1 (0.58) | POLBCYP1A2KMT2AKDM4EALDH1A1 | |
| SCHEMBL14701887 | 0.74 | DAO (0.56) | DAOPOLBMEN1CYP1A2KMT2A | |
| SCHEMBL5007826 | 0.72 | DAO (0.50) | DAOPOLBMEN1CYP1A2KMT2A | |
| SCHEMBL28257050 | 0.72 | CYP1A2 (0.54) | DAOPOLBMEN1CYP1A2KMT2A | |
| SCHEMBL11231429 | 0.71 | DAO (0.53) | DAOPOLBMEN1CYP1A2KMT2A | |
| SCHEMBL7058947 | 0.71 | MEN1 (0.56) | DAOPOLBMEN1CYP1A2KMT2A | |
| SCHEMBL31241488 | 0.71 | POLB (0.55) | POLBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11275907 | 0.70 | DAO (0.51) | DAOPOLBMEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990653-B1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |