Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583981 | 1.00 | MEN1 (0.58) | MEN1KMT2APOLBFGFR1MAPK1 | |
| SCHEMBL6832639 | 0.85 | MEN1 (0.49) | MEN1KMT2APOLBFGFR1NPC1 | |
| SCHEMBL6832637 | 0.85 | MEN1 (0.49) | MEN1KMT2APOLBFGFR1NPC1 | |
| Hydrochloric Acid SCHEMBL6835840 | 0.84 | MEN1 (0.48) | MEN1KMT2APOLBFGFR1NPC1 | |
| Hydrochloric Acid SCHEMBL6835843 | 0.84 | MEN1 (0.48) | MEN1KMT2APOLBFGFR1NPC1 | |
| SCHEMBL1962638 | 0.82 | MEN1 (0.84) | MEN1KMT2APOLB | |
| SCHEMBL1962640 | 0.82 | MEN1 (0.84) | MEN1KMT2APOLB | |
| SCHEMBL6583386 | 0.81 | KDM4E (0.64) | MEN1KMT2APOLBMAPK1HTT | |
| SCHEMBL6583378 | 0.81 | KDM4E (0.64) | MEN1KMT2APOLBMAPK1HTT | |
| SCHEMBL8550750 | 0.81 | KDM4E (0.64) | MEN1KMT2APOLBMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846689-B1 | Benzimidazole compounds | PFIZER (US) | 2004-01-14 | — | — | EP | claimed |
| EP-0846689-A1 | Benzimidazole compounds | PFIZER INC. (US) | 1998-06-10 | — | — | EP | claimed |
| EP-0846689-B1 | Benzimidazole compounds | PFIZER (US) | 2004-01-14 | — | — | EP | disclosed |
| EP-0846689-A1 | Benzimidazole compounds | PFIZER INC. (US) | 1998-06-10 | — | — | EP | disclosed |