Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796549 | 0.93 | GRM2 (0.45) | GRM2KDM4EMEN1KMT2AALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL6584038 | 0.92 | GRM2 (0.40) | GRM2DYRK3DYRK1ADYRK2DYRK1B | |
| SCHEMBL7787062 | 0.91 | DYRK1A (0.51) | GRM2DYRK3DYRK1ADYRK2DYRK1B | |
| SCHEMBL7793772 | 0.87 | DHODH (0.45) | KDM4EMEN1KMT2AALDH1A1POLB | |
| SCHEMBL6584296 | 0.87 | KMT2A (0.40) | GRM2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7590460 | 0.86 | DYRK1A (0.41) | GRM2DYRK3DYRK1ADYRK2DYRK1B | |
| SCHEMBL8741771 | 0.84 | DYRK3 (0.48) | GRM2DYRK3DYRK1ADYRK2DYRK1B | |
| SCHEMBL8741772 | 0.84 | TP53 (0.47) | GRM2DYRK3DYRK1ADYRK2DYRK1B | |
| SCHEMBL7020881 | 0.83 | MAPT (0.51) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8741605 | 0.82 | GRM2 (0.45) | GRM2KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778947-B1 | CHEMILUMINESCENT DETECTION OF HYDROLYTIC ENZYMES USING AN ACRIDAN | LUMIGEN INC (US) | 2004-05-12 | — | — | EP | disclosed |
| EP-0778946-B1 | NOVEL METHOD AND KITS FOR PRODUCING LIGHT FROM AN ACRIDAN COMPOUND | LUMIGEN INC (US) | 2002-10-23 | — | — | EP | disclosed |
| EP-0750748-B1 | NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 2001-12-05 | — | — | EP | disclosed |
| US-5750698-A | USEFUL IN DETECTING BOTH PEROXIDASE AND PEROXIDE | LUMIGEN, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5686258-A | Chemiluminescent detection of hydrolytic enzymes using an acridan | LUMIGEN, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| CN-1161083-A | Novel method and kits for producing light from 9,10-azetine compound | LUMIGEN INC (US) | 1997-10-01 | — | — | CN | disclosed |
| CN-1156506-A | Chemiluminescent detection using 9, 10-acridan hydrolase | LUMIGEN CO LTD (US) | 1997-08-06 | — | — | CN | disclosed |
| WO-1995023971-A1 | NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1995-09-08 | — | — | WO | disclosed |