Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795326 | 0.88 | KMT2A (0.44) | KMT2AMEN1LMNAKDM4EPDE10A | |
| SCHEMBL6584034 | 0.87 | GRM2 (0.45) | KMT2AMEN1LMNAKDM4EPOLB | |
| SCHEMBL7796549 | 0.87 | GRM2 (0.45) | KMT2AMEN1LMNAKDM4EPOLB | |
| SCHEMBL8686701 | 0.86 | DHODH (0.40) | KMT2AMEN1KDM4EMAPTGRM2 | |
| SCHEMBL8333267 | 0.84 | RAB9A (0.41) | KMT2AMEN1KDM4EPOLBMAPT | |
| SCHEMBL8686420 | 0.82 | ALDH1A1 (0.41) | KMT2AMEN1KDM4EPOLBMAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL6584038 | 0.80 | GRM2 (0.40) | KMT2AMEN1LMNAKDM4EPOLB | |
| SCHEMBL7047504 | 0.80 | KMT2A (0.47) | KMT2AMEN1KDM4EPOLBMAPT | |
| SCHEMBL7793772 | 0.79 | DHODH (0.45) | KMT2AMEN1LMNAKDM4EPOLB | |
| SCHEMBL7050407 | 0.77 | GRM2 (0.48) | KMT2AMEN1KDM4EPDE10APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778947-B1 | CHEMILUMINESCENT DETECTION OF HYDROLYTIC ENZYMES USING AN ACRIDAN | LUMIGEN INC (US) | 2004-05-12 | — | — | EP | disclosed |
| EP-0750748-B1 | NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 2001-12-05 | — | — | EP | disclosed |
| US-5750698-A | USEFUL IN DETECTING BOTH PEROXIDASE AND PEROXIDE | LUMIGEN, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5686258-A | Chemiluminescent detection of hydrolytic enzymes using an acridan | LUMIGEN, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| CN-1156506-A | Chemiluminescent detection using 9, 10-acridan hydrolase | LUMIGEN CO LTD (US) | 1997-08-06 | — | — | CN | disclosed |
| US-5593845-A | BY REACTION WITH PEROXIDES AND PEROXIDASE; DETECTION OF HAPTENS, PROTEINS, ANTIBODIES IN ENZYME IMMUNOASSAY | LUMIGEN, INC. (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1995023971-A1 | NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN, INC. (US) | 1995-09-08 | — | — | WO | disclosed |