Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.59 |
| ▸ | CCR1 | P32246 | 2/20 | 0.56 |
| ▸ | CTSK | P43235 | 6/20 | 0.50 |
| ▸ | CTSL | P07711 | 4/20 | 0.50 |
| ▸ | CTSB | P07858 | 4/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329754 | 1.00 | PREP (0.59) | PREPCCR1CTSKCTSLCTSB | |
| SCHEMBL6586390 | 1.00 | PREP (0.59) | PREPCCR1CTSKCTSLCTSB | |
| SCHEMBL11261467 | 0.88 | PREP (0.61) | PREPCCR1CTSKCTSLCTSB | |
| SCHEMBL8206098 | 0.88 | PREP (0.61) | PREPCCR1CTSKCTSLCTSB | |
| SCHEMBL8206101 | 0.88 | PREP (0.61) | PREPCCR1CTSKCTSLCTSB | |
| SCHEMBL11254461 | 0.88 | PREP (0.61) | PREPCCR1CTSKCTSLCTSB | |
| SCHEMBL9510140 | 0.86 | PREP (0.62) | PREPCCR1CTSKCTSLCTSB | |
| SCHEMBL7284618 | 0.84 | BCHE (0.57) | PREPCCR1CTSKCTSLCTSB | |
| SCHEMBL7159741 | 0.84 | ITGB3 (0.59) | PREPCCR1CTSKCTSLCTSB | |
| SCHEMBL7159739 | 0.84 | ITGB3 (0.59) | PREPCCR1CTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815080-B1 | DI-SUBSTITUTED 1,4-PIPERIDINE ESTERS AND AMIDES HAVING 5-HT4 ANTAGONISTIC ACTIVITY | BOEHRINGER INGELHEIM ITALIA (IT) | 2004-06-16 | — | — | EP | disclosed |