Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585536 | 0.95 | PPARG (0.56) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL6587026 | 0.94 | PPARG (0.54) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL6582928 | 0.94 | PPARG (0.53) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL6583699 | 0.94 | PPARG (0.53) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL6584166 | 0.94 | PPARG (0.53) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL6587658 | 0.92 | PPARG (0.52) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL6586247 | 0.88 | PPARG (0.48) | PPARGFFAR1KDRMAPTPPARA | |
| SCHEMBL6583863 | 0.87 | PPARG (0.54) | PPARGFFAR1MAPTPPARASMN1; SMN2 | |
| SCHEMBL6586492 | 0.86 | PPARG (0.47) | PPARGFFAR1KDRPPARA | |
| SCHEMBL6584573 | 0.86 | PPARG (0.49) | PPARGFFAR1KDRPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |