⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19910614 | 0.81 | — | — | |
| SCHEMBL801270 | 0.78 | — | — | |
| SCHEMBL3907850 | 0.76 | — | — | |
| SCHEMBL3909951 | 0.76 | — | — | |
| SCHEMBL1615800 | 0.76 | CHRNB2 (0.58) | — | |
| SCHEMBL1615790 | 0.76 | — | — | |
| SCHEMBL15793331 | 0.75 | CHRNB2 (0.52) | — | |
| SCHEMBL24079402 | 0.74 | — | — | |
| SCHEMBL24568579 | 0.74 | CHRNB2 (0.45) | — | |
| SCHEMBL22551833 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544176-B2 | Prodrugs of prostate specific membrane antigen (PSMA) inhibitor | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-01-28 | — | — | US | disclosed |
| US-10294243-B2 | Bicyclic compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-05-21 | — | — | US | disclosed |
| US-20170298090-A1 | Modulators of ROR-gamma Receptors, Composition and Use Thereof | KULING THERAPEUTICS (CN) | 2017-10-19 | — | — | US | disclosed |
| US-20170101422-A1 | Bicyclic compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-04-13 | — | — | US | disclosed |
| EP-2752206-A1 | MEDICAL INSTRUMENT | Terumo Kabushiki Kaisha (JP) | 2014-07-09 | — | — | EP | disclosed |
| US-20140171347-A1 | MEDICAL DEVICE | TERUMO KABUSHIKI KAISHA (JP) | 2014-06-19 | — | — | US | disclosed |
| EP-0784052-B1 | Quinoline derivatives as antagonists of leukotriene d4, compositions containing the same and processes for their preparation | AVENTIS HOLDINGS INC (US) | 2004-09-01 | — | — | EP | disclosed |
| EP-0784052-A1 | Quinoline derivatives as antagonists of leukotriene d4, compositions containing the same and processes for their preparation | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1997-07-16 | — | — | EP | disclosed |
| US-4920131-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4918081-A | Quinoline derivatives and use thereof as antagonists of leukotriene d4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-17 | — | — | US | disclosed |
| WO-1989012629-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-12-28 | — | — | WO | disclosed |
| EP-0348155-A1 | Quinoline derivatives as antagonists of leukotriene D4, compositions containing the same and processes for their preparation | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1989-12-27 | — | — | EP | disclosed |