SCHEMBL6584355

SCHEMBL6584355

COCCC(=O)N1CCC(CN2CCC(NC(=O)c3cc(Cl)c(N)cc3OC)CC2)CC1

nearest known ligand 0.87

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 3/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6586782 0.95 HTR4 (0.65) HTR4
SCHEMBL6586563 0.92 HTR4 (0.60) HTR4
SCHEMBL6587845 0.90 HTR4 (0.61) HTR4
SCHEMBL6583133 0.89 HTR4 (0.75) HTR4
SCHEMBL6586516 0.89 HTR4 (0.72) HTR4
SCHEMBL6584465 0.88 HTR4 (0.71) HTR4
SCHEMBL6584463 0.88 HTR4 (0.72) HTR4
SCHEMBL6588612 0.87 HTR4 (0.73) HTR4
SCHEMBL6586647 0.87 HTR4 (0.76) HTR4
SCHEMBL11545317 0.86 HTR4 (0.78) HTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1076055-B1 1- (1-SUBSTITUTED-4-PIPERIDINYL)METHYL]-4-PIPERIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES OF THESE COMPOUNDS DAINIPPON PHARMACEUTICAL CO (JP) 2004-11-24 EP claimed