Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331198 | 0.89 | FAAH (0.65) | FAAHHTR1AHTR7MCHR1DRD4 | |
| SCHEMBL17289123 | 0.89 | FAAH (0.65) | FAAHHTR1AHTR7MCHR1DRD4 | |
| SCHEMBL6584608 | 0.84 | FAAH (0.60) | FAAHHTR1AHTR7MCHR1DRD4 | |
| SCHEMBL1331611 | 0.81 | FAAH (0.58) | FAAHHTR1AHTR7MCHR1MEN1 | |
| SCHEMBL13041008 | 0.81 | FAAH (0.58) | FAAHHTR1AHTR7MCHR1MEN1 | |
| SCHEMBL1331766 | 0.81 | HRH3 (0.63) | FAAHHTR1AHTR7MCHR1DRD4 | |
| SCHEMBL17595034 | 0.80 | FAAH (0.56) | FAAHHTR1AHTR7MCHR1DRD4 | |
| SCHEMBL28824423 | 0.80 | FAAH (0.56) | FAAHHTR1AHTR7MCHR1DRD4 | |
| SCHEMBL30218414 | 0.79 | FAAH (0.67) | FAAHHTR1AHTR7MCHR1DRD4 | |
| SCHEMBL21043948 | 0.79 | FAAH (0.67) | FAAHHTR1AHTR7MCHR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102333568-A | Pharmaceutical compounds | BIAL PORTELA & CA SA | 2012-01-25 | — | — | CN | claimed |
| CN-103140478-A | Process for the synthesis of substituted urea compounds | BIAL PORTELA & CA SA | 2013-06-05 | — | — | CN | disclosed |
| CN-102333568-A | Pharmaceutical compounds | BIAL PORTELA & CA SA | 2012-01-25 | — | — | CN | disclosed |
| EP-0957100-B1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | KOWA CO (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6127360-A | ANTIHISTAMINES, ANTILEUKOTRIENES, ANTIINFLAMMATORY AGENTS, ANTIASTHMATIC AGENTS | KOWA CO., LTD. (JP) | 2000-10-03 | — | — | US | disclosed |
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |