Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 18/20 | 0.67 |
| ▸ | MAOA | P21397 | 17/20 | 0.67 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585538 | 0.99 | MAOB (0.68) | MAOBMAOAPDE3BPDE3AHTR1A | |
| SCHEMBL426467 | 0.94 | MAOB (0.70) | MAOBMAOAPDE3BPDE3AHTR1A | |
| SCHEMBL6583075 | 0.92 | MAOB (0.67) | MAOBMAOAPDE3BPDE3AHTR1A | |
| SCHEMBL6588324 | 0.89 | MAOB (0.70) | MAOBMAOA | |
| SCHEMBL13111961 | 0.88 | MAOB (0.65) | MAOBMAOAPDE3BPDE3AHTR1A | |
| SCHEMBL11273468 | 0.88 | MAOB (0.65) | MAOBMAOAPDE3BPDE3AHTR1A | |
| SCHEMBL11276922 | 0.88 | MAOB (0.65) | MAOBMAOAPDE3BPDE3AHTR1A | |
| SCHEMBL238817 | 0.87 | MAOB (0.72) | MAOBMAOA | |
| SCHEMBL29545160 | 0.87 | MAOB (0.72) | MAOBMAOA | |
| SCHEMBL8212260 | 0.87 | MAOB (0.72) | MAOBMAOADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957100-B1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | KOWA CO (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |