Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29545160 | 1.00 | MAOB (0.72) | MAOBMAOA | |
| SCHEMBL6588324 | 0.99 | MAOB (0.70) | MAOBMAOA | |
| SCHEMBL1040338 | 0.96 | MAOB (0.70) | MAOBMAOA | |
| SCHEMBL2842062 | 0.94 | MAOB (0.80) | MAOBMAOA | |
| SCHEMBL6585582 | 0.93 | MAOB (0.67) | MAOBMAOA | |
| SCHEMBL6001124 | 0.92 | MAOB (0.62) | MAOBMAOA | |
| SCHEMBL29935397 | 0.89 | MAOB (0.72) | MAOBMAOA | |
| SCHEMBL6585538 | 0.89 | MAOB (0.68) | MAOBMAOA | |
| SCHEMBL28843241 | 0.89 | MAOB (0.72) | MAOBMAOA | |
| SCHEMBL8212260 | 0.89 | MAOB (0.72) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104844585-B | Method for preparing brexpiprazole | 重庆医药工业研究院有限责任公司 | 2021-05-11 | — | — | CN | claimed |
| US-7777039-B2 | Process for the preparation of aripiprazole | ALEMBIC LIMITED (IN) | 2010-08-17 | — | — | US | claimed |
| WO-2007148191-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF ARIPIPRAZOLE | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2007-12-27 | — | — | WO | claimed |
| WO-2007118923-A1 | A PROCESS FOR THE PREPARATION OF ARIPIPRAZOLE AND INTERMEDIATES THEREOF | FERMION OY (FI) | 2007-10-25 | — | — | WO | claimed |
| WO-2007113846-A1 | A PROCESS FOR THE PREPARATION OF ARIPIPRAZOLE | ALEMBIC LIMITED (IN) | 2007-10-11 | — | — | WO | claimed |
| US-20070213535-A1 | Process for the manufacture of aripiprazole by using purified carbostyril compounds such as 7-(4-halobutoxy)-3,4-dihydro-2(1H)-quinolinones | CHEMAGIS LTD. (IL) | 2007-09-13 | — | — | US | claimed |
| US-20070149782-A1 | Methods of preparing a crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-2(1h)-quinolinone and the use thereof in the synthesis of Aripiprazole | CHEMAGIS LTD. (IL) | 2007-06-28 | — | — | US | claimed |
| US-20060258869-A1 | Process for the preparation of aripiprazole | ALEMBIC LIMITED (IN) | 2006-11-16 | — | — | US | claimed |
| US-20240024310-A1 | CARBOSTYRIL DERIVATIVES AND MOOD STABILIZERS FOR TREATING MOOD DISORDERS | OTSUKA PHARMA CO LTD (JP) | 2024-01-25 | — | — | US | disclosed |
| CN-117007701-A | Method for detecting genotoxic impurity aripiprazole intermediate in aripiprazole | 扬子江药业集团南京海陵药业有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-115594630-A | Preparation method of aripiprazole key intermediate | 北京万全德众医药生物技术有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-108069900-B | Preparation method and application of aripiprazole hydrochloride | 齐鲁制药有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-114689767-A | Method for detecting aripiprazole raw material and related substances of aripiprazole preparation | 丽珠医药集团股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114044772-A | Epipiprazole synthesis method and intermediate thereof | 浙江国邦药业有限公司 | 2022-02-15 | — | — | CN | disclosed |
| WO-2004060374-A1 | CARBOSTYRIL DERIVATIVES AND SEROTONIN REUPTAKE INHIBITORS FOR TREATMENT OF MOOD DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |
| EP-1419776-A2 | Low hygroscopic aripiprazole drug substance and processes for the preparation thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-20040058935-A1 | Crystals; storage stability; psychological disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
| EP-1330249-A1 | LOW HYGROSCOPIC ARIPIPRAZOLE DRUG SUBSTANCE AND PROCESSES FOR THE PREPARATION THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-30 | — | — | EP | disclosed |
| WO-2003026659-A1 | LOW HYGROSCOPIC ARIPIPRAZOLE DRUG SUBSTANCE AND PROCESSES FOR THE PREPARATION THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-04-03 | — | — | WO | disclosed |
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149782-A1 | Methods of preparing a crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-2(1h)-quinolinone and the use thereof in the synthesis of Aripiprazole | CYP2F1, CYP2A7, CYP2J2 | MAOB 123/4885MAOA 179/4885 |
| US-20070213535-A1 | Process for the manufacture of aripiprazole by using purified carbostyril compounds such as 7-(4-halobutoxy)-3,4-dihydro-2(1H)-quinolinones | CYP3A4, CYP2J2, CYP2A7 | MAOB 470/4885MAOA 590/4885 |
| US-20060258869-A1 | Process for the preparation of aripiprazole | CYP2F1, CYP3A4, CYP2A7 | MAOB 133/4885MAOA 260/4885 |
| US-20240024310-A1 | CARBOSTYRIL DERIVATIVES AND MOOD STABILIZERS FOR TREATING MOOD DISORDERS | DRD2, CHRNA6, GABRA6 | MAOB 135/4885MAOA 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.