Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584914 | 1.00 | PPARG (0.55) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6583452 | 0.98 | PPARG (0.53) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6583459 | 0.98 | PPARG (0.53) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6584211 | 0.86 | PPARG (0.57) | PPARGMTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL8888759 | 0.85 | PTPN1 (0.42) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6584250 | 0.85 | PPARG (0.58) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6973327 | 0.85 | PTPN1 (0.42) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6584259 | 0.85 | PPARG (0.58) | PPARGHDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL6583517 | 0.85 | PPARG (0.56) | PPARGHDAC1HDAC6MEN1KMT2A | |
| SCHEMBL6584599 | 0.85 | PPARG (0.39) | PPARGHDAC1HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |