Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584211 | 0.89 | PPARG (0.57) | PPARGMTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL6584914 | 0.85 | PPARG (0.55) | PPARGHDAC1HDAC6MTNR1AMTNR1B | |
| SCHEMBL6584904 | 0.85 | PPARG (0.55) | PPARGHDAC1HDAC6MTNR1AMTNR1B | |
| SCHEMBL6960498 | 0.85 | HDAC1 (0.45) | PPARGHDAC1HDAC6MTNR1AMTNR1B | |
| SCHEMBL6587576 | 0.85 | PPARG (0.58) | PPARGMTNR1AMTNR1BAPPABCB1 | |
| SCHEMBL6583521 | 0.85 | HDAC1 (0.43) | PPARGHDAC1HDAC6MTNR1AMTNR1B | |
| SCHEMBL6583459 | 0.83 | PPARG (0.53) | PPARGHDAC1HDAC6MTNR1AMTNR1B | |
| SCHEMBL6583452 | 0.83 | PPARG (0.53) | PPARGHDAC1HDAC6MTNR1AMTNR1B | |
| SCHEMBL6587646 | 0.82 | PPARG (0.59) | PPARGMTNR1AMTNR1BAPPABCB1 | |
| SCHEMBL8339459 | 0.81 | HDAC1 (0.43) | PPARGHDAC1HDAC6MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |