Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585289 | 1.00 | ALDH1A1 (0.59) | ALDH1A1KDM4ENPC1L3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL6581370 | 0.99 | ALDH1A1 (0.58) | ALDH1A1KDM4ENPC1L3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL6581363 | 0.99 | ALDH1A1 (0.58) | ALDH1A1KDM4ENPC1L3MBTL1KMT2A | |
| SCHEMBL8551275 | 0.83 | PDE10A (0.54) | ALDH1A1KDM4ENPC1L3MBTL1KMT2A | |
| SCHEMBL6582609 | 0.83 | MAPT (0.50) | ALDH1A1KDM4ENPC1L3MBTL1KMT2A | |
| SCHEMBL8551282 | 0.83 | PDE10A (0.54) | ALDH1A1KDM4ENPC1L3MBTL1KMT2A | |
| SCHEMBL6582603 | 0.83 | MAPT (0.50) | ALDH1A1KDM4ENPC1L3MBTL1KMT2A | |
| SCHEMBL6832779 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KDM4ENPC1L3MBTL1KMT2A | |
| SCHEMBL6832782 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KDM4ENPC1L3MBTL1KMT2A | |
| SCHEMBL6847238 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4ENPC1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846689-B1 | Benzimidazole compounds | PFIZER (US) | 2004-01-14 | — | — | EP | claimed |
| EP-0846689-B1 | Benzimidazole compounds | PFIZER (US) | 2004-01-14 | — | — | EP | disclosed |
| EP-0846689-A1 | Benzimidazole compounds | PFIZER INC. (US) | 1998-06-10 | — | — | EP | disclosed |