Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5878665 | 0.94 | PDE7A (0.61) | PDE7AALDH1A1POLBCCR2TXNRD1 | |
| SCHEMBL85544 | 0.87 | ALDH1A1 (0.58) | PDE7AALDH1A1HIF1APOLBMEN1 | |
| SCHEMBL27895137 | 0.81 | PDE7A (0.73) | PDE7AALDH1A1HIF1APOLBTXNRD1 | |
| SCHEMBL1114984 | 0.79 | ALDH1A1 (0.52) | PDE7AALDH1A1HIF1ATXNRD1TXNRD3 | |
| SCHEMBL31453603 | 0.79 | ALDH1A1 (0.52) | PDE7AALDH1A1HIF1ATXNRD1TXNRD3 | |
| SCHEMBL10184952 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HIF1ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL29748321 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HIF1ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL4427347 | 0.78 | ALDH1A1 (0.55) | PDE7AALDH1A1HIF1APOLBMEN1 | |
| SCHEMBL11433378 | 0.78 | PDE7A (0.57) | PDE7AALDH1A1POLBCCR2TXNRD1 | |
| SCHEMBL27912299 | 0.77 | PDE7A (0.59) | PDE7AALDH1A1HIF1APOLBTXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377550-A1 | PHENYL HETEROCYCLYL ETHER DERIVATIVES AS SEROTONIN RE-UPTAKE INHIBITORS | Pfizer Limited (GB) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002083643-A1 | PHENYL HETEROCYCLYL ETHER DERIVATIVES AS SEROTONIN RE-UPTAKE INHIBITORS | PFIZER LIMITED (GB) | 2002-10-24 | — | — | WO | disclosed |