Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858951 | 0.79 | SMN1; SMN2 (0.61) | ALDH1A1KMT2AMEN1USP2MKNK1 | |
| SCHEMBL17980285 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1USP2MKNK1 | |
| SCHEMBL13815700 | 0.76 | KMT2A (1.00) | ALDH1A1KMT2AMEN1USP2MKNK1 | |
| SCHEMBL6960706 | 0.75 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1USP2MKNK1 | |
| SCHEMBL28358875 | 0.75 | TNIK (0.45) | ALDH1A1KMT2AMEN1USP2TNIK | |
| SCHEMBL20575392 | 0.71 | CYP3A4 (0.59) | ALDH1A1KMT2AMEN1USP2MKNK1 | |
| SCHEMBL20064676 | 0.71 | ALDH1A1 (0.66) | ALDH1A1KMT2AMEN1USP2MKNK1 | |
| SCHEMBL14392676 | 0.71 | CYP2A6 (0.61) | PTK2RAB9ACYP2A6CYP11B1CYP11B2 | |
| SCHEMBL1852281 | 0.69 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1USP2MKNK1 | |
| SCHEMBL1506104 | 0.69 | CYP2A6 (0.55) | TNIKPTK2NPC1RAB9ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945440-B1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-05-26 | — | — | EP | disclosed |
| US-6180653-B1 | EATING DISORDERS; DIETETICS; ANTIDIABETIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0945440-A1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |