Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1428382 | 0.97 | — | — | |
| Bromide SCHEMBL10706961 | 0.71 | FDPS (0.31) | — | |
| SCHEMBL7110786 | 0.71 | FDPS (0.39) | — | |
| SCHEMBL123210 | 0.69 | — | — | |
| SCHEMBL437673 | 0.67 | FDPS (0.36) | — | |
| SCHEMBL2567591 | 0.67 | FDPS (0.36) | — | |
| SCHEMBL20811 | 0.67 | — | — | |
| SCHEMBL12641026 | 0.67 | FDPS (0.32) | — | |
| SCHEMBL11611288 | 0.67 | — | — | |
| Bromide SCHEMBL11873099 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024383-A | Preparation method of amiodarone hydrochloride | 广州瑞尔医药科技有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-115677928-B | Difunctional imidazolyl ionic liquid crosslinked copolymer, preparation method and catalytic application thereof | 浙江理工大学 | 2023-10-20 | — | — | CN | claimed |
| CN-101618033-A | New medical application of chromane compound HEF-05 | UNIV SHENYANG PHARMACEUTICAL | 2010-01-06 | — | — | CN | claimed |
| US-5702887-A | BENZ(B)ACRIDINIUM-12-CARBOXYLATE COMPOUNDS | CHIRON DIAGNOSTICS CORPORATION (US) | 1997-12-30 | — | — | US | claimed |
| US-20250122193-A1 | NOVEL PYRIDOCARBAZOLIUM COMPOUNDS AND MEDICAL USES THEREOF | LARSSON, Lars-Gunnar Olof (SE) | 2025-04-17 | — | — | US | disclosed |
| EP-4452268-A1 | NOVEL PYRIDOCARBAZOLIUM COMPOUNDS AND MEDICAL USES THEREOF | MyCural Therapeutics AB (SE) | 2024-10-30 | — | — | EP | disclosed |
| CN-117024383-A | Preparation method of amiodarone hydrochloride | 广州瑞尔医药科技有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-117024383-A | Preparation method of amiodarone hydrochloride | 广州瑞尔医药科技有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-115677928-B | Difunctional imidazolyl ionic liquid crosslinked copolymer, preparation method and catalytic application thereof | 浙江理工大学 | 2023-10-20 | — | — | CN | disclosed |
| WO-2023118893-A1 | NOVEL PYRIDOCARBAZOLIUM COMPOUNDS AND MEDICAL USES THEREOF | MYCURAL THERAPEUTICS (SE) | 2023-06-29 | — | — | WO | disclosed |
| CN-115677928-A | Difunctional imidazolyl ionic liquid cross-linked copolymer and preparation method and catalytic application thereof | 浙江理工大学 | 2023-02-03 | — | — | CN | disclosed |
| US-10059722-B2 | Cephalosporin derivatives and methods of use | UNIVERSITY OF KANSAS (US) | 2018-08-28 | — | — | US | disclosed |
| EP-1175419-B1 | ARYL SULFONYLS AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2003-05-28 | — | — | EP | disclosed |
| US-20030050315-A1 | Aryl sulfonyls as factor Xa inhibitors | WEXLER RUTH R (US) | 2003-03-13 | — | — | US | disclosed |
| US-6399644-B1 | ANTICOAGULANTS | DUPONT PHARMACEUTICALS COMPANY | 2002-06-04 | — | — | US | disclosed |
| EP-1175419-A2 | ARYL SULFONYLS AS FACTOR XA INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2002-01-30 | — | — | EP | disclosed |
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| WO-2000059902-A2 | ARYL SULFONYLS AS FACTOR XA INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
| US-5384232-A | Process for rapid access development of silver halide films using pyridinium as development accelerators | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-24 | — | — | US | disclosed |