Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 14/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583141 | 0.91 | NAMPT (0.51) | NAMPTALDH1A1GLP1RSMN1; SMN2 | |
| SCHEMBL6580507 | 0.90 | NAMPT (0.65) | NAMPTSMN1; SMN2POLB | |
| SCHEMBL6790569 | 0.89 | NAMPT (0.66) | NAMPTALDH1A1 | |
| SCHEMBL6582111 | 0.88 | NAMPT (0.54) | NAMPTALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL6582624 | 0.88 | NAMPT (0.52) | NAMPTALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL6582965 | 0.87 | NAMPT (0.52) | NAMPTALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL6902914 | 0.84 | NAMPT (0.73) | NAMPT | |
| SCHEMBL6583938 | 0.84 | NAMPT (0.67) | NAMPT | |
| SCHEMBL6583098 | 0.82 | NAMPT (0.66) | NAMPT | |
| SCHEMBL6582182 | 0.82 | NAMPT (0.63) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155012-B1 | ANTI-CANCER DIHYDROQUINAZOLINE DERIVATIVES | CANCER REC TECH LTD (GB) | 2004-04-14 | — | — | EP | disclosed |
| US-6699861-B1 | ANTI-CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2004-03-02 | — | — | US | disclosed |