Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 11/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580888 | 0.84 | SCD (0.43) | SCDGRIN2BEPHX2 | |
| SCHEMBL6582400 | 0.83 | SCD (0.41) | SCDGRIN2BBDKRB1 | |
| SCHEMBL6582862 | 0.80 | SCD (0.43) | SCDGRIN2BEPHX2FAAH | |
| SCHEMBL5409925 | 0.77 | GRIN2B (0.55) | SCDGRIN2BEPHX2FAAH | |
| SCHEMBL5399467 | 0.76 | GRIN2B (0.58) | SCDGRIN2BEPHX2FAAH | |
| SCHEMBL5398252 | 0.75 | SCD (0.44) | SCDEPHX2FAAH | |
| SCHEMBL5412796 | 0.74 | SCD (0.45) | SCDGRIN2BEPHX2FAAH | |
| SCHEMBL6580878 | 0.73 | SCD (0.44) | SCD | |
| SCHEMBL6586187 | 0.71 | SCD (0.45) | SCD | |
| Hydrochloric Acid SCHEMBL6584529 | 0.70 | ROCK2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455788-A1 | 1-GLYCINYL-4-AMINOMETHYL-PIPERIDINE DERIVATIVES AS FACTOR XA INHIBITORS | ELI LILLY AND COMPANY (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003049737-A1 | CHEMICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |