Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 6/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 7/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL658419 | 0.80 | SMPD2 (0.37) | SMPD1CNR1 | |
| SCHEMBL659074 | 0.79 | EPHX1 (0.40) | — | |
| SCHEMBL659630 | 0.73 | KLKB1 (0.49) | KLKB1KDM4E | |
| SCHEMBL27699443 | 0.70 | CNR1 (0.54) | KLKB1SMPD1CNR1CNR2KDM4E | |
| SCHEMBL27727992 | 0.68 | CNR2 (0.49) | CNR1CNR2 | |
| SCHEMBL10625859 | 0.67 | CNR1 (0.41) | CNR1CNR2 | |
| SCHEMBL12506457 | 0.67 | CNR1 (0.44) | CNR1CNR2KDM4EPOLBTSHR | |
| SCHEMBL28943994 | 0.67 | CNR1 (0.50) | KLKB1CNR1CNR2KDM4EPOLB | |
| SCHEMBL29006267 | 0.66 | ALDH1A1 (0.43) | KLKB1KDM4EPOLBTSHR | |
| SCHEMBL21503702 | 0.66 | CNR1 (0.40) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046301-A1 | Substituted Cyclic Carboxamide and Urea Derivatives as Ligands of the Vanilloid Receptor | GRUENENTHAL GMBH (DE) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046301-A1 | Substituted Cyclic Carboxamide and Urea Derivatives as Ligands of the Vanilloid Receptor | TRPV1, CNR1, CNR2 | KLKB1 4444/4885SMPD1 3470/4885CNR1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.