Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27288656 | 0.81 | MDM2 (0.43) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL31113844 | 0.75 | KDM1A (0.60) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL7509163 | 0.75 | KDM1A (0.60) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL27298262 | 0.75 | HTR2A (0.50) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL7509170 | 0.75 | KDM1A (0.60) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL6991920 | 0.75 | KDM1A (0.60) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL2837243 | 0.75 | KDM1A (0.60) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL6991918 | 0.75 | KDM1A (0.60) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL16591166 | 0.75 | HTR2A (0.50) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL2835482 | 0.75 | KDM1A (0.60) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104039753-A | Compositions, synthesis, and methods of using phenylcycloalkylmethylamine derivatives | REVIVA PHARMACEUTICALS INC | 2014-09-10 | — | — | CN | disclosed |
| EP-1390354-A1 | TRIAZINYL ACRYLAMIDE DERIVATIVES AS KINASE INHIBITORS | Amgen Inc. (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002083653-A1 | TRIAZINYL ACRYLAMIDE DERIVATIVES AS KINASE INHIBITORS | AMGEN INC. (US) | 2002-10-24 | — | — | WO | disclosed |