Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586419 | 0.81 | HTR2A (0.50) | MDM2HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL16451639 | 0.73 | HTR2A (0.47) | MDM2HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL4000922 | 0.73 | MDM2 (0.43) | MDM2HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL15291807 | 0.73 | HTR2A (0.47) | MDM2HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL19771738 | 0.73 | MDM2 (0.43) | MDM2HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL15282173 | 0.73 | HTR2A (0.47) | MDM2HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL17806041 | 0.73 | HTR2A (0.47) | MDM2HTR2AHTR2CHTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL16372230 | 0.71 | HTR2A (0.50) | MDM2HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL19775354 | 0.68 | MDM2 (0.44) | MDM2SLC6A3SLC6A4 | |
| SCHEMBL20749174 | 0.68 | HTR2A (0.47) | HTR2AHTR2CHTR2BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1012733-B | Process for the preparation of therapeutic agents | BOOTS CO PLC (GB) | 1991-06-05 | — | — | CN | disclosed |
| CN-86100954-A | The preparation method of therapeutical agent and application | — | 1986-09-03 | — | — | CN | disclosed |