Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151147 | 0.96 | MEN1 (0.58) | MEN1KMT2AALDH1A1TSHRUSP2 | |
| Fumaric Acid SCHEMBL10499430 | 0.86 | TSHR (0.51) | MEN1KMT2AALDH1A1TSHRUSP2 | |
| Fumaric Acid SCHEMBL10499414 | 0.86 | TSHR (0.51) | MEN1KMT2AALDH1A1TSHRUSP2 | |
| SCHEMBL10498998 | 0.85 | MEN1 (0.66) | MEN1KMT2AALDH1A1TSHRUSP2 | |
| SCHEMBL9687018 | 0.85 | SLC6A9 (0.60) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10498575 | 0.84 | MEN1 (0.72) | MEN1KMT2AALDH1A1TSHRUSP2 | |
| SCHEMBL10498885 | 0.84 | MEN1 (0.61) | MEN1KMT2AALDH1A1TSHRUSP2 | |
| SCHEMBL9204768 | 0.84 | MEN1 (0.63) | MEN1KMT2AALDH1A1TSHRUSP2 | |
| SCHEMBL10499011 | 0.83 | MEN1 (0.63) | MEN1KMT2AALDH1A1TSHRUSP2 | |
| SCHEMBL10499179 | 0.82 | MEN1 (0.61) | MEN1KMT2AALDH1A1TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957100-B1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | KOWA CO (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |
| EP-0507696-B1 | Antihistaminic and non-sedative derivatives of benzimidazol, process for their preparation and their medicinal use | ESTEVE LABOR DR (ES) | 1995-08-09 | — | — | EP | disclosed |
| US-5214040-A | Side effect reduction | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1993-05-25 | — | — | US | disclosed |
| EP-0507696-A1 | Antihistaminic and non-sedative derivatives of benzimidazol, process for their preparation and their medicinal use | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1992-10-07 | — | — | EP | disclosed |
| EP-0123962-B1 | BENZIMIDAZOLE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION | KANEBO, LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |
| US-4603130-A | ANTIHISTAMINES | KANEBO, LTD. (JP) | 1986-07-29 | — | — | US | disclosed |
| EP-0123962-A2 | Benzimidazole derivative, process for the preparation thereof and pharmaceutical composition | KANEBO, LTD. (JP) | 1984-11-07 | — | — | EP | disclosed |