Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 5/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584900 | 0.82 | CTSK (0.46) | CTSKKCNA3CA1CA2HSD11B1 | |
| SCHEMBL6588968 | 0.81 | CTSK (0.45) | CTSKKCNA3CA1CA2HSD11B1 | |
| SCHEMBL6586597 | 0.81 | CTSK (0.44) | CTSKKCNA3CA1CA2HSD11B1 | |
| SCHEMBL6586538 | 0.79 | CTSK (0.43) | CTSKKCNA3CA1CA2HSD11B1 | |
| SCHEMBL6587799 | 0.79 | SLC6A2 (0.31) | KDM5A | |
| SCHEMBL6586301 | 0.76 | CTSK (0.41) | CTSKKCNA3CA1CA2HSD11B1 | |
| SCHEMBL6585663 | 0.76 | CTSK (0.40) | CTSKKCNA3CA1CA2HSD11B1 | |
| SCHEMBL6580060 | 0.75 | KCNA3 (0.47) | CTSKKCNA3DRD2 | |
| SCHEMBL6590305 | 0.75 | KCNA3 (0.46) | CTSKKCNA3DRD2PARP1KDM5A | |
| SCHEMBL27081047 | 0.74 | CTSK (0.48) | CTSKKCNA3CA1CA2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076055-B1 | 1- (1-SUBSTITUTED-4-PIPERIDINYL)METHYL]-4-PIPERIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES OF THESE COMPOUNDS | DAINIPPON PHARMACEUTICAL CO (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6294555-B1 | SEROTONIN HT3 RECEPTOR ANTAGONIST FOR GASTROINTESTINAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1076055-A1 | 1- (1-SUBSTITUTED-4-PIPERIDINYL)METHYL]-4-PIPERIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES OF THESE COMPOUNDS | Dainippon Pharmaceutical Co., Ltd. (JP) | 2001-02-14 | — | — | EP | disclosed |