Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684123 | 1.00 | LOXL2 (0.68) | LOXL2MAPTSLC6A4TAAR1SLC6A2 | |
| SCHEMBL10662499 | 1.00 | LOXL2 (0.68) | LOXL2MAPTSLC6A4TAAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL8186555 | 0.98 | LOXL2 (0.66) | LOXL2MAPTSLC6A4TAAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL11403569 | 0.98 | LOXL2 (0.66) | LOXL2MAPTSLC6A4TAAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL8881330 | 0.98 | LOXL2 (0.66) | LOXL2MAPTSLC6A4TAAR1SLC6A2 | |
| SCHEMBL765010 | 0.85 | LOXL2 (0.61) | LOXL2MAPTCYP4A11CYP4F2CA1 | |
| SCHEMBL18920591 | 0.84 | LOXL2 (0.61) | LOXL2MAPTCYP4A11CYP4F2SLC7A5 | |
| SCHEMBL27827214 | 0.84 | LOXL2 (0.61) | LOXL2MAPTCYP4A11CYP4F2SLC7A5 | |
| SCHEMBL21144955 | 0.84 | LOXL2 (0.61) | LOXL2MAPTCYP4A11CYP4F2SLC7A5 | |
| SCHEMBL9498956 | 0.84 | TAAR1 (0.52) | LOXL2SLC6A4TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481899-A1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | The University of Massachusetts (US) | 2019-05-15 | — | — | EP | claimed |
| CN-109415553-A | The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin | 马萨诸塞大学 | 2019-03-01 | — | — | CN | claimed |
| WO-2018008003-A1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | THE UNIVERSITY OF MASSACHUSETTS (US) | 2018-01-11 | — | — | WO | claimed |
| EP-3481899-B1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | UNIV MASSACHUSETTS (US) | 2022-12-21 | — | — | EP | disclosed |
| US-11414384-B2 | P300/CBP hat inhibitors | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2022-08-16 | — | — | US | disclosed |
| EP-3752250-B1 | P300/CBP HAT INHIBITORS | CONSTELLATION PHARMACEUTICALS INC (US) | 2022-08-03 | — | — | EP | disclosed |
| US-20210061762-A1 | P300/CBP HAT INHIBITORS | CONSTELLATION PHARMACEUTICALS, INC. | 2021-03-04 | — | — | US | disclosed |
| US-20210061762-A1 | P300/CBP HAT INHIBITORS | CONSTELLATION PHARMACEUTICALS, INC. | 2021-03-04 | — | — | US | disclosed |
| US-10913844-B2 | Plasticized thermoset resin, and associated cured resin, method of curing, and article comprising cured resin | THE UNIVERSITY OF MASSACHUSETTS (US) | 2021-02-09 | — | — | US | disclosed |
| EP-3752250-A1 | P300/CBP HAT INHIBITORS | Constellation Pharmaceuticals, Inc. (US) | 2020-12-23 | — | — | EP | disclosed |
| US-20190309159-A1 | PLASTICIZED THERMOSET RESIN, AND ASSOCIATED CURED RESIN, METHOD OF CURING, AND ARTICLE COMPRISING CURED RESIN | THE UNIVERSITY OF MASSACHUSETTS | 2019-10-10 | — | — | US | disclosed |
| US-4385066-A | DIETETICS, HYPERGLYCEMIC AGENTS ANTIINFLAMMATORY AGENTS | BEECHAM GROUP LIMITED (GB) | 1983-05-24 | — | — | US | disclosed |
| EP-0028105-B1 | SECONDARY AMINES, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1983-01-19 | — | — | EP | disclosed |
| EP-0061907-A1 | Secondary amines, their preparation, pharmaceutical compositions containing them and their use | BEECHAM GROUP PLC (GB) | 1982-10-06 | — | — | EP | disclosed |
| US-4341793-A | HYPOGLYCEMIC AGENTS AND DIETETICS | BEECHAM GROUP LIMITED (GB) | 1982-07-27 | — | — | US | disclosed |
| US-4329358-A | 3-Chlorophenyl anti-obesity agents | BEECHAM GROUP LIMITED (GB) | 1982-05-11 | — | — | US | disclosed |
| EP-0040915-A1 | Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-12-02 | — | — | EP | disclosed |
| EP-0029320-A2 | Secondary ethanol amines, their preparation and their use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-05-27 | — | — | EP | disclosed |
| EP-0028105-A1 | Secondary amines, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-05-06 | — | — | EP | disclosed |
| EP-0006735-A1 | Secondary amines, their preparation, pharmaceutical compositions containing them and their use | BEECHAM GROUP PLC (GB) | 1980-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11414384-B2 | P300/CBP hat inhibitors | EP300, HDAC1, KAT2A | LOXL2 2317/4885MAPT 887/4885SLC6A4 4392/4885 |
| US-20210061762-A1 | P300/CBP HAT INHIBITORS | EP300, HDAC1, KAT2A | LOXL2 2317/4885MAPT 887/4885SLC6A4 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.