Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11346600 | 1.00 | CYP2C19 (0.52) | CYP2C19SLC1A3SLC1A2SLC1A1LMNA | |
| SCHEMBL7421923 | 0.91 | CYP2C19 (0.40) | CYP2C19SLC1A3SLC1A2SLC1A1LMNA | |
| SCHEMBL1053596 | 0.87 | CYP2C19 (0.45) | CYP2C19LMNAARG1 | |
| SCHEMBL27206940 | 0.83 | CYP2C19 (0.36) | CYP2C19SLC1A3SLC1A2SLC1A1LMNA | |
| SCHEMBL23045194 | 0.83 | CYP2C19 (0.37) | CYP2C19LMNAEPHX1ARG1 | |
| SCHEMBL29953092 | 0.82 | CYP2C19 (0.38) | CYP2C19SLC1A3SLC1A2SLC1A1LMNA | |
| SCHEMBL10624868 | 0.77 | CYP2C19 (0.33) | CYP2C19SLC1A3SLC1A2SLC1A1LMNA | |
| SCHEMBL6055016 | 0.77 | CYP2C19 (0.35) | CYP2C19 | |
| SCHEMBL15437 | 0.76 | CYP2C19 (0.33) | CYP2C19 | |
| SCHEMBL10789382 | 0.76 | CYP2C19 (0.41) | CYP2C19LMNATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990653-B1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |