Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | GRM8 | O00222 | 1/20 | 0.30 |
| ▸ | GRM6 | O15303 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421923 | 0.91 | CYP2C19 (0.40) | CYP2C19LMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1053596 | 0.91 | CYP2C19 (0.45) | CYP2C19LMNAPLGPLATALDH1A1 | |
| SCHEMBL16211144 | 0.85 | CYP2C19 (0.32) | CYP2C19 | |
| SCHEMBL13281154 | 0.85 | GABRA5 (0.35) | CYP2C19TSHRARG1 | |
| SCHEMBL5809445 | 0.85 | CYP2C19 (0.32) | CYP2C19 | |
| SCHEMBL11346600 | 0.82 | CYP2C19 (0.52) | CYP2C19LMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6586703 | 0.82 | CYP2C19 (0.52) | CYP2C19LMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27206940 | 0.79 | CYP2C19 (0.36) | CYP2C19LMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5081028 | 0.78 | HSD11B1 (0.44) | LMNAPLGPLATSLC1A3SLC1A2 | |
| SCHEMBL14323007 | 0.78 | HSD11B1 (0.33) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |