Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586776 | 0.85 | ANPEP (0.40) | ANPEPENPEP | |
| SCHEMBL8232419 | 0.77 | ANPEP (0.42) | ANPEPENPEPMEN1KMT2AKDM4E | |
| SCHEMBL19981639 | 0.72 | POLB (0.41) | MEN1KMT2ATSHRNPSR1CARM1 | |
| SCHEMBL469155 | 0.71 | CARM1 (0.52) | KDM4ECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL19981797 | 0.68 | SIGMAR1 (0.41) | MEN1KMT2ATSHRNPSR1ALDH1A1 | |
| SCHEMBL19972726 | 0.68 | SIGMAR1 (0.41) | MEN1KMT2ATSHRNPSR1ALDH1A1 | |
| SCHEMBL21294392 | 0.68 | SIGMAR1 (0.41) | MEN1KMT2ATSHRNPSR1ALDH1A1 | |
| SCHEMBL19972739 | 0.68 | SIGMAR1 (0.41) | MEN1KMT2ATSHRNPSR1ALDH1A1 | |
| SCHEMBL21669271 | 0.67 | — | — | |
| SCHEMBL22958012 | 0.66 | PHGDH (0.46) | MEN1KMT2AALDH1A1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815080-B1 | DI-SUBSTITUTED 1,4-PIPERIDINE ESTERS AND AMIDES HAVING 5-HT4 ANTAGONISTIC ACTIVITY | BOEHRINGER INGELHEIM ITALIA (IT) | 2004-06-16 | — | — | EP | disclosed |