Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.77 |
| ▸ | FNTB | P49356 | 10/20 | 0.77 |
| ▸ | RORC | P51449 | 9/20 | 0.58 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13529456 | 0.87 | FNTA (1.00) | FNTAFNTBRORCPGGT1B | |
| SCHEMBL5783176 | 0.81 | FNTA (0.69) | FNTAFNTBRORC | |
| Hydrochloric Acid SCHEMBL6010278 | 0.81 | FNTA (0.90) | FNTAFNTBRORCPGGT1B | |
| SCHEMBL5657968 | 0.81 | FNTA (0.87) | FNTAFNTBRORCPGGT1B | |
| SCHEMBL5783981 | 0.80 | FNTA (0.68) | FNTAFNTBRORC | |
| SCHEMBL5659938 | 0.80 | FNTA (0.85) | FNTAFNTBRORCPGGT1B | |
| Hydrochloric Acid SCHEMBL5656573 | 0.80 | FNTA (0.85) | FNTAFNTBRORCPGGT1B | |
| SCHEMBL5781212 | 0.80 | FNTA (0.67) | FNTAFNTBRORC | |
| SCHEMBL1682772 | 0.80 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL13928075 | 0.80 | FNTA (1.00) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420015-A1 | Imidazolyl derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2004-05-19 | — | — | EP | disclosed |
| EP-1097150-B1 | IMIDAZOLYL DERIVATIVES | CONSEILS DE RECH SET D APPLIC (FR) | 2004-03-24 | — | — | EP | disclosed |
| US-20040002531-A1 | Imidazolyl derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATION SCIENTEFIQUES, S.A.S., A FRANCE CORPORATION | 2004-01-01 | — | — | US | disclosed |
| US-6509336-B1 | Prenyl transeferase inhibitors | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2003-01-21 | — | — | US | disclosed |
| US-20030004342-A1 | Imidazolyl derivatives | BIOMEASURE, INC., A MASSACHUSETTS CORPORATION | 2003-01-02 | — | — | US | disclosed |
| US-6420555-B1 | IMIDAZOLE DERIVATIVES PRENYL TRANSFERASE INHIBITORS. | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2002-07-16 | — | — | US | disclosed |
| EP-1097150-A1 | IMIDAZOLYL DERIVATIVES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2001-05-09 | — | — | EP | disclosed |
| EP-1094810-A1 | USE OF PRENYLTRANSFERASE INHIBITORS FOR PREPARING A MEDICINE FOR TREATING PATHOLOGIES RESULTING FROM HETEROTRIMERIC G PROTEIN MEMBRANE FIXATION | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002558-A1 | USE OF PRENYLTRANSFERASE INHIBITORS FOR PREPARING A MEDICINE FOR TREATING PATHOLOGIES RESULTING FROM HETEROTRIMERIC G PROTEIN MEMBRANE FIXATION | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-01-20 | — | — | WO | disclosed |
| WO-1999065898-A1 | IMIDAZOLYL DERIVATIVES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES SAS (FR) | 1999-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004342-A1 | Imidazolyl derivatives | TPI1, BCHE, CYP51A1 | FNTA 51/4885FNTB 184/4885RORC 1358/4885 |
| US-20040002531-A1 | Imidazolyl derivatives | TPI1, BCHE, CYP51A1 | FNTA 51/4885FNTB 184/4885RORC 1358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.