Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.40 |
| ▸ | PDE4A | P27815 | 5/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582898 | 0.83 | PPARG (0.53) | ALDH1A1HTTPDE4BPDE4APDE4C | |
| SCHEMBL6588197 | 0.81 | PDE4B (0.41) | ALDH1A1HTTPDE4BPDE4APDE4C | |
| SCHEMBL6585871 | 0.77 | PDE4A (0.61) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6582595 | 0.76 | PDE4B (0.55) | ALDH1A1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6585923 | 0.76 | PDE4B (0.55) | ALDH1A1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6584615 | 0.75 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6588285 | 0.74 | HIF1A (0.45) | ALDH1A1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6585601 | 0.74 | PDE4B (0.42) | ALDH1A1HTTPDE4BPDE4APDE4C | |
| SCHEMBL6586912 | 0.73 | PDE4B (0.46) | ALDH1A1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6586764 | 0.73 | PDE4B (0.46) | ALDH1A1PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |