Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.46 |
| ▸ | PDE4A | P27815 | 5/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582898 | 0.86 | PPARG (0.53) | PDE4BPDE4DPDE4APDE4CALDH1A1 | |
| SCHEMBL6586764 | 0.84 | PDE4B (0.46) | PDE4BPDE4DPDE4APDE4CALDH1A1 | |
| SCHEMBL6588285 | 0.83 | HIF1A (0.45) | PDE4BPDE4DPDE4APDE4CALDH1A1 | |
| SCHEMBL6582744 | 0.83 | SIGMAR1 (0.50) | — | |
| SCHEMBL7914446 | 0.82 | NFKB1 (0.60) | PDE4BPDE4DPDE4APDE4CSMPD1 | |
| SCHEMBL6586702 | 0.82 | FFAR1 (0.45) | PDE4BPDE4DPDE4APDE4CPPARD | |
| SCHEMBL10080328 | 0.82 | SMPD1 (0.48) | PDE4BPDE4DPDE4APDE4CSMPD1 | |
| SCHEMBL6584615 | 0.81 | PDE4B (0.60) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7333971 | 0.80 | SMPD1 (0.50) | PDE4BPDE4DPDE4APDE4CSMPD1 | |
| SCHEMBL6584079 | 0.80 | PDE4B (0.43) | PDE4BPDE4DPDE4APDE4CSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |