SCHEMBL658714

SCHEMBL658714

COC1C(O)[C@@H](CO)O[C@H]1n1cnc2c(O)ncnc21

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
ADORA3 P0DMS8 4/20 0.59
ADORA1 P30542 3/20 0.58
SLC29A1 Q99808 2/20 0.57
DPP4 P27487 1/20 0.57
SLC28A1 O00337 1/20 0.57
MAP3K7 O43318 1/20 0.57
SLC28A2 O43868 1/20 0.57
GAPDH P04406 1/20 0.57
MAPK1 P28482 1/20 0.57
ADORA2A P29274 1/20 0.57
ADORA2B P29275 1/20 0.57
STAT6 P42226 1/20 0.57
PI4KA P42356 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
PI4K2B Q8TCG2 1/20 0.57
DOT1L Q8TEK3 1/20 0.57
PI4K2A Q9BTU6 1/20 0.57
SLC28A3 Q9HAS3 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20995821 1.00 MEN1 (0.66) MEN1KMT2AADORA3ADORA1SLC29A1
SCHEMBL658713 1.00 MEN1 (0.66) MEN1KMT2AADORA3ADORA1SLC29A1
SCHEMBL29406864 1.00 MEN1 (0.66) MEN1KMT2AADORA3ADORA1SLC29A1
SCHEMBL29409681 0.99 MEN1 (0.65) MEN1KMT2AADORA3ADORA1SLC29A1
SCHEMBL31000830 0.91 MEN1 (0.56) MEN1KMT2AADORA3ADORA1SLC29A1
SCHEMBL25238463 0.91 ADORA3 (0.57) MEN1KMT2AADORA3ADORA1SLC29A1
SCHEMBL29771414 0.89 ADORA1 (0.56) MEN1KMT2AADORA3ADORA1SLC29A1
SCHEMBL887800 0.89 ADORA1 (0.56) MEN1KMT2AADORA3ADORA1SLC29A1
SCHEMBL1059414 0.89 ADORA1 (0.56) MEN1KMT2AADORA3ADORA1SLC29A1
SCHEMBL14764094 0.89 ADORA1 (0.58) MEN1KMT2AADORA3ADORA1SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2287 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090085-A1 TREATMENT OF CD33 RELATED DISEASES AND DISORDERS EMPIRICO INC. (US) 2026-04-30 WO claimed
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 EP claimed
US-20260043025-A1 RNAi Agents And Compositions for Inhibiting Expression of Apolipoprotein C-III (APOC3) ARROWHEAD PHARMACEUTICALS INC (US) 2026-02-12 US claimed
US-20260009037-A1 RNAi Agents for Inhibiting Expression of Mitochondrial Amidoxime Reducing Component 1 (MARC1), Pharmaceutical Compositions Thereof, and Methods of Use ARROWHEAD PHARMACEUTICALS INC (US) 2026-01-08 US claimed
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 EP claimed
EP-4627082-A1 TREATMENT OF MTRES1 RELATED DISEASES AND DISORDERS EMPIRICO INC. (US) 2025-10-08 EP claimed
US-20250283089-A1 TREATMENT OF A NON-ALCOHOLIC FATTY LIVER DISEASE ARROWHEAD PHARMACEUTICALS INC (US) 2025-09-11 US claimed
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
EP-4601656-A1 MODIFIED OLIGONUCLEOTIDES Pharmorage Pty Limited (AU) 2025-08-20 EP claimed
US-12365899-B2 RNAi agents and compositions for inhibiting expression of apolipoprotein C-III (APOC3) Arrowhead Pharmaceuticals, Inc. (US) 2025-07-22 US claimed
US-9719084-B2 Co-transcriptional assembly of modified RNA nanoparticles THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2017-08-01 US claimed
US-9249173-B2 Compounds and pharmaceutical compositions for the treatment of viral infections IDENIX PHARMACEUTICALS, LLC (US) 2016-02-02 US claimed
US-20150203842-A1 CO-TRANSCRIPTIONAL ASSEMBLY OF MODIFIED RNA NANOPARTICLES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES 2015-07-23 US claimed
US-20140315762-A1 METHODS FOR TAGGING DNA-ENCODED LIBRARIES X-CHEM, INC. (US) 2014-10-23 US claimed
EP-2578685-A2 RNA containing modified nucleosides and methods of use thereof The Trustees of The University of Pennsylvania (US) 2013-04-10 EP claimed
US-7807653-B2 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2010-10-05 US claimed
US-20090307805-A1 ALTERNATIVE NUCLEOTIDES FOR IMPROVED TARGETED NUCLEOTIDE EXCHANGE KEYGENE N.V 2009-12-10 US claimed
US-20070265224-A1 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2007-11-15 US claimed
US-20040059104-A1 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2004-03-25 US claimed
US-4130641-A Induction of interferon production by modified nucleic acid complexes HEM RESEARCH, INC. 1978-12-19 US claimed