Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865466 | 0.92 | ALDH1A1 (0.56) | MAPTSMN1; SMN2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL29888697 | 0.84 | SMN1; SMN2 (0.71) | MAPTSMN1; SMN2ALDH1A1HSD17B10LMNA | |
| SCHEMBL10760227 | 0.80 | MAPT (0.60) | MAPTSMN1; SMN2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL5266012 | 0.80 | NPSR1 (0.69) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL10760234 | 0.80 | MAPT (0.60) | MAPTSMN1; SMN2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11108446 | 0.79 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL944312 | 0.79 | POLB (0.72) | MAPTSMN1; SMN2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL9431194 | 0.79 | MAPT (0.67) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL10761379 | 0.78 | POLB (0.53) | MAPTSMN1; SMN2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL7867868 | 0.78 | MAPT (0.66) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815455-B1 | ANTIFOAM AGENTS OF MACROPHAGES; PREVENTING ARTERIOSCLEROSIS | FUJI PHOTO FILM CO., LTD. (JP) | 2004-11-09 | — | — | US | disclosed |
| EP-1197487-B1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2004-01-14 | — | — | EP | disclosed |
| EP-1197487-A1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | Fuji Photo Film Co., Ltd. (JP) | 2002-04-17 | — | — | EP | disclosed |