Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473402 | 0.92 | ADRB1 (0.65) | ADRB1HTR1AALDH1A1LMNACYP3A4 | |
| SCHEMBL13239004 | 0.77 | ADRB1 (0.71) | ADRB1HTR1AALDH1A1LMNACYP3A4 | |
| SCHEMBL31051961 | 0.76 | ADRB1 (0.69) | ADRB1HTR1AALDH1A1LMNACYP3A4 | |
| SCHEMBL31051847 | 0.74 | ADRB1 (0.67) | ADRB1HTR1AALDH1A1LMNACYP3A4 | |
| SCHEMBL31052065 | 0.74 | ADRB1 (0.67) | ADRB1HTR1AALDH1A1LMNACYP3A4 | |
| SCHEMBL31052066 | 0.74 | ADRB1 (0.67) | ADRB1HTR1AALDH1A1LMNACYP3A4 | |
| SCHEMBL2203340 | 0.74 | ADRB1 (0.67) | ADRB1HTR1AALDH1A1LMNACYP3A4 | |
| Eltoprazine SCHEMBL177715 | 0.74 | ADRB1 (1.00) | ADRB1HTR1AALDH1A1LMNACYP3A4 | |
| SCHEMBL13499602 | 0.74 | ADRB1 (0.67) | ADRB1HTR1AALDH1A1LMNACYP3A4 | |
| SCHEMBL31052020 | 0.74 | ADRB1 (0.67) | ADRB1HTR1AALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861837-B1 | 2-Aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2004-04-28 | — | — | EP | disclosed |
| US-5968954-A | EXHIBIT SELECTIVE BINDING AFFINITY FOR 5-HYDROXYTRYPTAMINE RECEPTORS | ADIR ET COMPAGNIE (FR) | 1999-10-19 | — | — | US | disclosed |
| EP-0861837-A1 | 2-Aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-09-02 | — | — | EP | disclosed |