Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | RAF1 | P04049 | 2/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899122 | 0.96 | PPARG (0.55) | PPARGMTNR1AMTNR1BAPPSIRT2 | |
| SCHEMBL8889627 | 0.91 | PPARG (0.50) | PPARGMTNR1AMTNR1BAPPSIRT2 | |
| SCHEMBL6583544 | 0.89 | SIRT2 (0.59) | PPARGMTNR1AMTNR1BAPPSIRT2 | |
| SCHEMBL6587021 | 0.83 | PPARG (0.75) | PPARGMAPTCYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL6583684 | 0.83 | SIRT2 (0.47) | PPARGMTNR1AMTNR1BAPPSIRT2 | |
| SCHEMBL6582922 | 0.83 | PPARG (0.74) | PPARGMAPTCYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL6584159 | 0.83 | PPARG (0.74) | PPARGMAPTCYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL6583693 | 0.83 | PPARG (0.74) | PPARGMAPTCYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL6587576 | 0.82 | PPARG (0.58) | PPARGMTNR1AMTNR1BAPPSIRT2 | |
| SCHEMBL6583517 | 0.82 | PPARG (0.56) | PPARGMTNR1AMTNR1BAPPSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |