Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5723604 | 0.86 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL5723554 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6724346 | 0.82 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL5727670 | 0.78 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL5723498 | 0.77 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL5723507 | 0.77 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL5723529 | 0.76 | PTGS2 (0.75) | PTGS2PTGS1 | |
| SCHEMBL5723316 | 0.76 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL5723269 | 0.75 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL6725693 | 0.74 | PTGS2 (0.76) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406609-A2 | SUBSTITUTED ARYL COMPOUNDS AS NOVEL CYCLOOXYGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND METHODS OF USE | Nitromed, Inc. (US) | 2004-04-14 | — | — | EP | claimed |
| EP-1406609-A4 | SUBSTITUTED ARYL COMPOUNDS AS NOVEL CYCLOOXYGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED INC (US) | 2004-04-14 | — | — | EP | claimed |
| WO-2002060378-A2 | SUBSTITUTED ARYL COMPOUNDS AS CYCLOOXYGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2002-08-08 | — | — | WO | claimed |