Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594120 | 0.87 | CTSL (0.30) | CTSLCTSSCTSK | |
| SCHEMBL6595810 | 0.85 | — | — | |
| SCHEMBL6590719 | 0.81 | — | — | |
| SCHEMBL6486966 | 0.79 | HPGD (0.39) | CTSLCTSSCTSK | |
| SCHEMBL6590892 | 0.77 | CTSL (0.32) | CTSLCTSSCTSK | |
| SCHEMBL6594868 | 0.77 | CTSL (0.31) | CTSLCTSSCTSK | |
| SCHEMBL6589602 | 0.76 | CTSL (0.32) | CTSLCTSSCTSK | |
| SCHEMBL6865999 | 0.76 | — | — | |
| SCHEMBL6587967 | 0.74 | — | — | |
| SCHEMBL6476464 | 0.74 | EPHX2 (0.36) | CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1413580-A1 | Furanone derivatives as inhibitors of Cathepsin S | Medivir UK Ltd (GB) | 2004-04-28 | — | — | EP | claimed |
| EP-1178986-B1 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LTD (GB) | 2004-02-25 | — | — | EP | claimed |
| EP-1413580-A1 | Furanone derivatives as inhibitors of Cathepsin S | Medivir UK Ltd (GB) | 2004-04-28 | — | — | EP | disclosed |