Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.37 |
| ▸ | PROC | P04070 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448254 | 0.88 | F10 (0.65) | F10KLKB1CFD | |
| SCHEMBL3830205 | 0.87 | F10 (0.76) | F10KLKB1 | |
| SCHEMBL3832343 | 0.81 | F10 (0.58) | F10 | |
| SCHEMBL4096033 | 0.74 | F10 (0.47) | F10KLKB1CFD | |
| SCHEMBL8467091 | 0.74 | F10 (0.76) | F10F2KLKB1PRSS1 | |
| SCHEMBL3830395 | 0.74 | F10 (0.61) | F10 | |
| SCHEMBL4848578 | 0.73 | F10 (0.49) | F10KLKB1CFD | |
| SCHEMBL3833575 | 0.73 | F10 (0.78) | F10HSD17B3KLKB1 | |
| SCHEMBL4102479 | 0.73 | F10 (0.88) | F10KLKB1CFD | |
| SCHEMBL3833576 | 0.73 | F10 (0.78) | F10HSD17B3KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465864-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | Warner-Lambert Company LLC (US) | 2004-10-13 | — | — | EP | claimed |
| WO-2003045912-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2003-06-05 | — | — | WO | claimed |