Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.65 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.44 |
| ▸ | CFD | P00746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830205 | 0.93 | F10 (0.76) | F10KLKB1 | |
| SCHEMBL6588775 | 0.88 | F10 (0.56) | F10KLKB1CFD | |
| SCHEMBL8467091 | 0.87 | F10 (0.76) | F10KLKB1 | |
| SCHEMBL8450077 | 0.86 | F10 (0.87) | F10KLKB1 | |
| SCHEMBL8459600 | 0.86 | F10 (0.65) | F10KLKB1CFD | |
| SCHEMBL14039623 | 0.80 | F10 (0.64) | F10 | |
| SCHEMBL3833575 | 0.80 | F10 (0.78) | F10KLKB1 | |
| SCHEMBL3833576 | 0.80 | F10 (0.78) | F10KLKB1 | |
| SCHEMBL4102479 | 0.80 | F10 (0.88) | F10KLKB1CFD | |
| SCHEMBL3829980 | 0.80 | F10 (0.87) | F10KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7407974-B2 | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade | PFIZER INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-20050250815-A1 | Inhibitors of fractor Xa and other serine proteases involved in the coagulation cascade | WARNER-LAMBERT COMPANY LLC | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250815-A1 | Inhibitors of fractor Xa and other serine proteases involved in the coagulation cascade | F12, TFPI, F11 | F10 9/4885KLKB1 120/4885CFD 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.