SCHEMBL6589097

SCHEMBL6589097

CCOC(=O)CN1CCN(Cc2ccc3c(Cl)c(C(=O)Nc4ccc(Cl)cc4C(=O)Nc4ccc(Cl)cc4)sc3c2)CC1

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.80
F2 P00734 7/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6592630 0.89 F10 (1.00) F10F2
SCHEMBL6590730 0.88 F10 (1.00) F10F2
SCHEMBL6593051 0.83 F10 (0.77) F10F2
SCHEMBL6590651 0.79 F10 (1.00) F10
SCHEMBL6592115 0.78 F10 (1.00) F10F2
SCHEMBL6592263 0.78 F10 (0.71) F10
SCHEMBL6591190 0.74 F10 (1.00) F10F2
SCHEMBL6589476 0.74 F10 (1.00) F10F2
SCHEMBL6588004 0.73 F10 (1.00) F10F2
SCHEMBL6590441 0.72 F10 (1.00) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1040108-B1 ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS SCHERING AG (DE) 2004-02-25 EP disclosed
US-6498185-B1 ENZYME FACTOR XA INHIBITORS BERLEX LABORATORIES, INC. 2002-12-24 US disclosed
US-6140351-A FOR TREATING THROMBOSIS BERLEX LABORATORIES, INC. (US) 2000-10-31 US disclosed