Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592115 | 0.83 | F10 (1.00) | F10MAPK1PRSS12 | |
| SCHEMBL6590651 | 0.82 | F10 (1.00) | F10 | |
| SCHEMBL6590565 | 0.80 | F10 (0.63) | F10 | |
| SCHEMBL6591302 | 0.79 | F10 (0.77) | F10 | |
| SCHEMBL6590730 | 0.79 | F10 (1.00) | F10 | |
| SCHEMBL6589097 | 0.78 | F10 (0.80) | F10 | |
| SCHEMBL6590441 | 0.77 | F10 (1.00) | F10PRSS12 | |
| SCHEMBL6592630 | 0.76 | F10 (1.00) | F10MAPK1 | |
| SCHEMBL6591396 | 0.74 | F10 (1.00) | F10 | |
| SCHEMBL2724506 | 0.73 | PRSS12 (0.74) | F10MAPK1PRSS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | claimed |
| US-6380221-B1 | FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY | BERLEX LABORATORIES, INC. | 2002-04-30 | — | — | US | claimed |
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6498185-B1 | ENZYME FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. | 2002-12-24 | — | — | US | disclosed |
| US-6380221-B1 | FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY | BERLEX LABORATORIES, INC. | 2002-04-30 | — | — | US | disclosed |
| US-6140351-A | FOR TREATING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-10-31 | — | — | US | disclosed |