Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.60 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.60 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.60 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434494 | 0.91 | CACNA1F (0.62) | CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7381359 | 0.90 | CACNA1F (0.61) | CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11521180 | 0.90 | CACNA1F (0.61) | CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7431826 | 0.90 | CACNA1C (0.71) | CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11729940 | 0.89 | CACNA1F (0.60) | CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL10739765 | 0.85 | — | — | |
| SCHEMBL11732555 | 0.85 | CACNA1F (0.60) | CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11688212 | 0.85 | CACNA1C (0.63) | CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9765702 | 0.85 | CACNA1C (0.66) | CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11869125 | 0.85 | CACNA1C (0.66) | CACNA1FCACNA1DCACNA1SCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689799-B1 | NON-NUCLEOSIDE-DERIVATIVE VIRICIDES | REPHARTOX (NL) | 2004-02-10 | — | — | US | disclosed |
| EP-1214315-B9 | 1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID ESTER DERIVATIVES AND METHOD FOR THE PREPARATION THEREOF | REPHARTOX (NL) | 2004-01-02 | — | — | EP | disclosed |
| EP-1214315-B1 | 1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID ESTER DERIVATIVES AND METHOD FOR THE PREPARATION THEREOF | REPHARTOX (NL) | 2003-05-02 | — | — | EP | disclosed |
| EP-1214315-A1 | 1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID ESTER DERIVATIVES AND METHOD FOR THE PREPARATION THEREOF | Rephartox (NL) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001014370-A1 | 1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID ESTER DERIVATIVES AND METHOD FOR THE PREPARATION THEREOF | REPHARTOX (NL) | 2001-03-01 | — | — | WO | disclosed |