Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.47 |
| ▸ | CTSB | P07858 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548947 | 0.85 | NPC1 (0.45) | CTSLCTSBALDH1A1CTSSCTSK | |
| SCHEMBL5525937 | 0.83 | CTSL (0.67) | CTSLCTSBCTSSCTSK | |
| SCHEMBL5525932 | 0.83 | CTSL (0.67) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7112566 | 0.82 | CTSL (0.42) | CTSLCTSBCTSSCTSKPPARG | |
| SCHEMBL6019209 | 0.81 | CTSL (0.67) | CTSLCTSBCTSSCTSKCTSF | |
| SCHEMBL6020007 | 0.81 | CTSL (0.51) | CTSLCTSBMEN1ALDH1A1LMNA | |
| SCHEMBL6021764 | 0.78 | CTSL (0.64) | CTSLCTSBCTSSCTSKCTSF | |
| SCHEMBL5517750 | 0.78 | CTSL (0.64) | CTSLCTSBCTSSCTSKCTSF | |
| SCHEMBL5529192 | 0.76 | HPGD (0.56) | CTSLCTSBMEN1LMNAHTT | |
| SCHEMBL3622043 | 0.76 | ACE (0.39) | CTSLCTSBMEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178958-B1 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARM INC (US) | 2004-02-18 | — | — | EP | claimed |