Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591147 | 0.89 | CA1 (0.54) | CA1CA2CA12CA7CA14 | |
| SCHEMBL6591449 | 0.86 | ABCC9 (0.42) | CA1CA2CA12CA7CA14 | |
| SCHEMBL6594026 | 0.84 | HCRTR1 (0.34) | PIN1HCRTR1HCRTR2HIF1A | |
| SCHEMBL6592791 | 0.84 | ABCC9 (0.37) | PIN1HCRTR1HCRTR2HIF1ASMN1; SMN2 | |
| SCHEMBL6590513 | 0.83 | MALT1 (0.49) | CA1CA2CA12CA7CA14 | |
| SCHEMBL4253427 | 0.82 | HCRTR1 (0.34) | PIN1HCRTR1HCRTR2HIF1A | |
| SCHEMBL6592058 | 0.82 | HIF1A (0.50) | PIN1HCRTR1HCRTR2HIF1ASMN1; SMN2 | |
| SCHEMBL6592710 | 0.77 | CA1 (0.44) | CA1CA2CA12CA7CA14 | |
| SCHEMBL6594278 | 0.75 | ABCC9 (0.53) | CA1CA2CA12CA7CA14 | |
| SCHEMBL6593174 | 0.74 | ABCC9 (0.44) | CA1CA2CA12CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842927-B1 | 3-Amido-chromanylsulfonyl(thio)ureas, process for their preparation, their use and medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-5849755-A | 3-amidochromanylsulfonyl(thio)ureas, processes for their preparation, their use, and pharmaceutical preparations comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0842927-A1 | 3-Amido-chromanylsulfonyl(thio)ureas, process for their preparation, their use and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-20 | — | — | EP | disclosed |