Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4690381 | 0.77 | CTSK (0.75) | CTSKCTSLCTSBCTSSTAS1R3 | |
| SCHEMBL4690508 | 0.77 | CTSK (0.74) | CTSKCTSLCTSBCTSSTAS1R3 | |
| SCHEMBL14345772 | 0.77 | CTSK (0.64) | CTSKCTSLCTSBCTSSTAS1R3 | |
| SCHEMBL5743949 | 0.76 | CTSK (0.57) | CTSKCTSLCTSBCTSSTAS1R3 | |
| SCHEMBL4765813 | 0.75 | CTSK (0.73) | CTSKCTSLCTSBCTSSUTS2R | |
| SCHEMBL5093131 | 0.75 | CTSK (0.73) | CTSKCTSLCTSBCTSSTAS1R3 | |
| SCHEMBL12632224 | 0.72 | CYP1A2 (0.53) | HRH3CYP1A2 | |
| SCHEMBL4690446 | 0.72 | CTSK (0.67) | CTSKCTSLCTSBCTSSPPARG | |
| SCHEMBL4689513 | 0.72 | CTSK (0.67) | CTSKCTSLCTSBCTSS | |
| SCHEMBL15765652 | 0.71 | CTSK (1.00) | CTSKCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-1158986-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |
| EP-1158986-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000038687-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |