SCHEMBL6589559

SCHEMBL6589559

CSc1nc2c(Cl)cc(F)c(-c3nn(C)c(C(F)(F)F)c3Cl)c2s1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 1/20 0.31
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6587324 0.85 MEN1 (0.30)
SCHEMBL6592617 0.84 SMN1; SMN2 (0.37)
SCHEMBL6590185 0.81
SCHEMBL6590416 0.80 MAPT (0.38) MAPTMAPK1
SCHEMBL7507013 0.76
SCHEMBL6280669 0.73 MEN1 (0.33) MAPT
SCHEMBL6590842 0.71 MAPT (0.30) MAPT
SCHEMBL6283333 0.70
SCHEMBL8331898 0.69 KDR (0.36) GLP1R
SCHEMBL6283851 0.69 ADORA3 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0944623-B1 SUBSTITUTED PYRAZOLE-3-YL BENZAZOLES BASF AG (DE) 2004-09-01 EP disclosed
US-6232470-B1 AGRICULTURE BASF AKTIENGESELLSCHAFT (DE) 2001-05-15 US disclosed
CN-1244865-A Substituted pyrazole-3-yl benzazoles BASF AK (DE) 2000-02-16 CN disclosed
EP-0944623-A2 SUBSTITUTED PYRAZOLE-3-YL BENZAZOLES BASF AKTIENGESELLSCHAFT (DE) 1999-09-29 EP disclosed
WO-1998027090-A2 SUBSTITUTED PYRAZOLE-3-YL BENZAZOLES BASF AKTIENGESELLSCHAFT (DE) 1998-06-25 WO disclosed