Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 7/20 | 0.33 |
| ▸ | CA2 | P00918 | 7/20 | 0.33 |
| ▸ | CA9 | Q16790 | 7/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6191964 | 0.94 | ALOX15 (0.56) | ALOX15KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL6502302 | 0.82 | KDM4E (0.58) | ALOX15KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL6506713 | 0.81 | TSHR (0.56) | ALOX15KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL6503320 | 0.81 | TSHR (0.56) | ALOX15KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL6501752 | 0.81 | TSHR (0.56) | ALOX15KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL6503378 | 0.81 | TSHR (0.56) | ALOX15KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL15789606 | 0.79 | KMT2A (0.55) | ALOX15KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL16451626 | 0.79 | KMT2A (0.55) | ALOX15KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL16444883 | 0.79 | KMT2A (0.55) | ALOX15KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL16444884 | 0.79 | KMT2A (0.55) | ALOX15KDM4EUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823423-B1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| CN-1188471-A | 1,4-disubstituted piepridine derivatives | BANYU PHARMA CO LTD (JP) | 1998-07-22 | — | — | CN | disclosed |
| US-5750540-A | SIDE EFFECT REDUCTION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0823423-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |